Acetone potentiation of 1,1,2-trichloroethane hepatotoxicity by john robert macdonald a thesis submitted to the faculty of the committee on toxicology (graduate) in partial fulfillment of the requirements for the degree of master of science in the graduate college. This is to certify that the research work, embodied in this thesis entitled “ association of oxidative stress and genetic polymorphisms of gstm1, gstt1 and cyp2e1 with anti-tuberculosis drug induced hepatotoxicity in north indian population” has been undertaken by the candidate ms khushboo ambreen this is to further. With hepatotoxicity collectively, the results indicate that the aqueous extract of spathodea campanulata is fairly nontoxic and may exhibit hepatoprotective activity at lower doses by enhancing antioxidant protection in the cell and inhibiting total cytochrome p450 hence interfering with bioactivation of hepatotoxic agents. Hepatotoxicity to bht metabolism, with toxicity varying with species (eg rats also, a decision- point approach to hepatotoxicity tests was performed on rat hepatocytes: a histological and ultrastructural study m sc thesis university of kuwait babich h (1982) butylated hydroxytoluene (bht): a review environ res. Recent developments in the field of in vitro hepatotoxicity include three- dimensional tissue constructs and bioartificial livers, co-cultures of various cell types with hepatocytes, and differentiation of stem cells into hepatic lineage-like cells in an attempt to provide a more physiological environment for cultured. Gene expression profiling in primary rat hepatocytes for the prediction of hepatotoxicity vom fachbereich biologie der technischen universität darmstadt zur erlangung des akademischen grades eines doctor rerum naturalium genehmigte dissertation von dipl ing (fh) birthe lauer aus worms berichterstatter (1.
2014 (english)in: european journal of clinical pharmacology, issn 0031-6970, e-issn 1432-1041, vol 70, no 4, 501-503 particle in journal, letter (refereed) published place, publisher, year, edition, pages 2014 vol 70, no 4, 501-503 p national category pharmacology and toxicology identifiers. Follow this and additional works at: http://iruiowaedu/etd part of the toxicology commons recommended citation klaren, william delbert assessment of hepatic micronutrient disruption and the hepatotoxicity of 3,3',4,4',5- pentachlorobiphenyl (pcb126) phd (doctor of philosophy) thesis, university of iowa, 2016. Of pharmacology and toxicology, toxicology research center and medicinal plants research center, ahvaz jundishapur university of medical sciences, ahvaz, iran abstract in the present study, protective effect of teucrium polium l (labiatae) extract on acetaminophen-induced hepatotoxicity was investigated in mice.
Hepatotoxicity in which different mechanisms may be responsible, and these are discussed clinical and tions of ecstasy or amphetamine-induced hepatotoxicity makes a recognition of the aetiological agent difficult thesis of heat shock proteins in rat liver after ischaemia and hyperthermia hepatol 1985 5 : 357±61. Induced hepatotoxicity in male albino rat administration of mulberry ethanolic extract (mul) leaves against hepatotoxic effect of the anti-rheumatic drug thesis one of the major reasons for a decline in biosyn- thetic functions is the low protein feeding diet however, hence animals in the present study were fed a diet.
The role of mitochondria in the potential hepatotoxicity caused by cadmium telluride quantum dot nanoparticles by kathy c nguyen a thesis submitted to the faculty of graduate and postdoctoral affairs in partial fulfillment of the requirements for the degree of doctor of philosophy in biology, specialization in chemical. After acetaminophen treatment, histology showed no significant differences in hepatotoxicity acetaminophen induced an ap- proximate 5-fold induction of no synthesis (serum nitrate plus nitrite) in wild type mice, and the increase in serum nitrate plus nitrite paralleled increases in serum alt increased no syn- thesis was. Herbal remedies are an important and often-used commodity in developing countries, such as those in africa there is a long-standing belief that these medicinal preparations are more effective and safe than allopathic medications due to their natural origins however, very little information is available to describe the.